Edwin K Silverman Selected Research

Emphysema

1/2022	Association of clonal hematopoiesis with chronic obstructive pulmonary disease.
1/2022	Interstitial Lung Abnormalities, Emphysema, and Spirometry in Smokers.
7/2021	Secondary polycythemia in chronic obstructive pulmonary disease: prevalence and risk factors.
4/2021	Soluble receptor for advanced glycation end products (sRAGE) as a biomarker of COPD.
1/2021	Hedgehog interacting protein-expressing lung fibroblasts suppress lymphocytic inflammation in mice.
1/2021	Markers of disease activity in COPD: an 8-year mortality study in the ECLIPSE cohort.
5/2020	Validation of a method to assess emphysema severity by spirometry in the COPDGene study.
1/2020	Luminal Plugging on Chest CT Scan: Association With Lung Function, Quality of Life, and COPD Clinical Phenotypes.
1/2020	Machine Learning Characterization of COPD Subtypes: Insights From the COPDGene Study.
11/2019	Pulmonary Subtypes Exhibit Differential Global Initiative for Chronic Obstructive Lung Disease Spirometry Stage Progression: The COPDGene® Study.

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Edwin K Silverman Research Topics

Disease

197	Chronic Obstructive Pulmonary Disease (COPD) 11/2022 - 01/2003
67	Emphysema 01/2022 - 07/2007
41	Asthma (Bronchial Asthma) 04/2022 - 12/2002
14	Lung Diseases (Lung Disease) 03/2022 - 10/2005
13	Inflammation (Inflammations) 01/2022 - 02/2005
8	Dyspnea (Shortness of Breath) 10/2018 - 08/2007
7	Chronic Bronchitis 01/2020 - 03/2002
4	Hypoxia (Hypoxemia) 07/2021 - 03/2009
4	Neoplasms (Cancer) 01/2021 - 07/2013
4	Obstructive Lung Diseases (Obstructive Lung Disease) 10/2020 - 03/2012
3	Disease Progression 08/2016 - 03/2007
3	Lung Injury 02/2016 - 03/2007
2	Bronchiectasis 01/2022 - 09/2010
2	Interstitial Lung Diseases (Interstitial Lung Disease) 01/2022 - 03/2012
2	Weight Loss (Weight Reduction) 12/2021 - 05/2020
2	Fibrosis (Cirrhosis) 08/2021 - 03/2012
2	Pulmonary Arterial Hypertension 01/2021 - 11/2020
2	Cardiovascular Diseases (Cardiovascular Disease) 01/2021 - 11/2019
2	Atherosclerosis 12/2019 - 01/2018
2	Hypertension (High Blood Pressure) 01/2019 - 01/2016
2	Lymphangioleiomyomatosis (Lymphangiomyomatosis) 01/2019 - 07/2013
2	Idiopathic Pulmonary Fibrosis 01/2019 - 01/2016
2	Tuberous Sclerosis (Bourneville's Disease) 01/2019 - 07/2013
2	Adenocarcinoma of Lung 05/2017 - 01/2014
2	Pneumonia (Pneumonitis) 02/2016 - 03/2012
2	Pulmonary Fibrosis (Fibrosing Alveolitis) 02/2015 - 03/2012
2	Hypersensitivity (Allergy) 08/2014 - 02/2004
2	Severe Early-Onset Chronic Obstructive Pulmonary Disease 06/2009 - 10/2005
2	Hemochromatosis (Bronze Diabetes) 08/2007 - 05/2004
1	Atopic Dermatitis (Atopic Eczema) 12/2021
1	COVID-19 10/2021

Drug/Important Bio-Agent (IBA)

56	Biomarkers (Surrogate Marker)IBA 01/2022 - 03/2007
43	GoldIBA 07/2022 - 02/2010
29	Proteins (Proteins, Gene)FDA Link 04/2022 - 02/2006
28	SmokeIBA 03/2022 - 11/2004
24	Bronchodilator Agents (Bronchodilators)IBA 07/2017 - 05/2003
14	Biological ProductsIBA 04/2022 - 12/2003
11	Immunoglobulin E (IgE)IBA 04/2022 - 04/2002
7	RNA (Ribonucleic Acid)IBA 04/2022 - 01/2017
7	DNA (Deoxyribonucleic Acid)IBA 01/2021 - 01/2003
7	Pharmaceutical PreparationsIBA 11/2020 - 03/2005
7	Pulmonary Surfactant-Associated Protein D (Surfactant Protein D)IBA 11/2019 - 03/2011
7	Adrenal Cortex Hormones (Corticosteroids)IBA 01/2016 - 01/2004
6	Oxygen (Dioxygen)IBA 07/2021 - 03/2009
6	Fibrinogen (Factor I)FDA Link 11/2019 - 11/2011
6	nasIBA 10/2018 - 03/2009
5	Receptor for Advanced Glycation End ProductsIBA 04/2021 - 10/2013
5	IronIBA 05/2020 - 05/2004
5	C-Reactive ProteinIBA 05/2020 - 12/2012
4	Interleukin-6 (Interleukin 6)IBA 01/2018 - 11/2011
4	Interleukin-8 (Interleukin 8)IBA 01/2018 - 09/2013
4	ElastinIBA 01/2017 - 10/2005
4	Messenger RNA (mRNA)IBA 01/2016 - 10/2009
3	CalciumIBA 04/2022 - 08/2014
3	Blood Proteins (Serum Proteins)IBA 12/2021 - 08/2016
3	Genetic Markers (Genetic Marker)IBA 11/2020 - 03/2010
3	Surface-Active Agents (Surfactants)IBA 11/2019 - 07/2005
3	CholesterolIBA 01/2019 - 03/2012
3	SteroidsIBA 01/2018 - 01/2004
3	Transcription Factors (Transcription Factor)IBA 12/2017 - 02/2015
3	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 12/2012 - 07/2005
3	Albuterol (Salbutamol)FDA LinkGeneric 08/2012 - 02/2004
3	Serpin E2IBA 09/2011 - 07/2007
3	AllergensIBA 03/2007 - 04/2002
3	Methacholine Chloride (Methacholine)FDA Link 01/2006 - 08/2003
2	Carbon MonoxideIBA 01/2022 - 07/2021
2	P-2 (P 2)IBA 11/2021 - 12/2010
2	alpha 1-Antitrypsin (alpha 1 Antitrypsin)IBA 08/2021 - 04/2003
2	CytokinesIBA 01/2021 - 10/2017
2	ChromatinIBA 01/2021 - 01/2019
2	Histone Deacetylases (Histone Deacetylase)IBA 11/2020 - 12/2013
2	Mitogen-Activated Protein KinasesIBA 10/2020 - 01/2019
2	Phenobarbital (Luminal)FDA Link 01/2020 - 08/2009
2	UteroglobinIBA 11/2019 - 12/2012
2	lipoarabinomannan (LAM)IBA 01/2019 - 07/2013
2	Metalloproteases (Metalloproteinases)IBA 11/2018 - 06/2004
2	Interleukin-13IBA 10/2018 - 07/2007
2	Nicotine FDA Link 12/2017 - 02/2012
2	ChemokinesIBA 10/2017 - 05/2011
2	Iron Regulatory Protein 2IBA 02/2016 - 10/2009
2	Prednisolone (Predate)FDA LinkGeneric 01/2016 - 05/2011
2	GlucocorticoidsIBA 06/2015 - 05/2015
2	antineoplaston A10 (A 10)IBA 02/2014 - 08/2010
2	Nitric Oxide Synthase (NO Synthase)IBA 11/2013 - 08/2003
2	Cholinergic Agents (Cholinergics)IBA 02/2012 - 12/2010
2	Plasminogen InactivatorsIBA 09/2011 - 07/2007
2	Protease Inhibitors (Protease Inhibitor)IBA 11/2010 - 04/2003
2	LigandsIBA 09/2009 - 02/2006
2	Transforming Growth Factor beta (TGF-beta)IBA 09/2009 - 05/2006
2	Epoxide HydrolasesIBA 03/2009 - 05/2006
2	Interleukin-10 (Interleukin 10)IBA 01/2008 - 02/2004
2	DefensinsIBA 12/2006 - 02/2005
2	Transforming Growth Factor beta1 (TGF beta 1)IBA 05/2006 - 08/2004
2	IgA receptor (protein B)IBA 05/2006 - 07/2005
1	ApoferritinsIBA 12/2021
1	Interleukin-33IBA 12/2021

Therapy/Procedure

16	Therapeutics 07/2021 - 02/2004
8	Precision Medicine 11/2022 - 08/2016
3	Pneumonectomy (Lung Volume Reduction) 01/2018 - 08/2007
1	Traction 01/2022